10/11/2023 0 Comments Back to the future 3 reviewMany aspects of this gut-brain-skin unifying theory have recently been validated. Among the remedies advocated by Stokes and Pillsbury were Lactobacillus acidophilus cultures. Stokes and Pillsbury hypothesized that emotional states might alter the normal intestinal microflora, increase intestinal permeability and contribute to systemic inflammation. Pillsbury first proposed a gastrointestinal mechanism for the overlap between depression, anxiety and skin conditions such as acne. Over 70 years have passed since dermatologists John H.
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